If you’re looking for the ultimate comfort food casserole that’s creamy, cheesy, and bursting with savory flavor, this Chicken Bubble Biscuit Bake Casserole is the answer. Imagine tender chunks of chicken, buttery biscuits that bubble up into golden perfection, and a rich, creamy sauce laced with cheese and seasonings — all baked into one irresistible dish. It’s hearty, family-friendly, and guaranteed to become a weeknight favorite.
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🧈 Why You’ll Love This Chicken Bubble Biscuit Bake
This casserole is everything you love about homemade comfort food — with minimal effort. It combines shredded chicken, flaky biscuits, creamy soup, and melted cheese into a dish that’s both satisfying and fuss-free. Perfect for busy weeknights, potlucks, or cozy Sunday dinners, this recipe delivers a delicious, made-from-scratch taste with simple pantry staples.
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🥘 Ingredients and Their Roles
Main Ingredients
2 cups cooked chicken (shredded or diced): The star of the dish. You can use rotisserie chicken for convenience or leftover baked chicken for deeper flavor.
1 can (10.5 oz) cream of chicken soup: Adds the creamy, velvety base that binds the casserole together. It provides rich flavor and moisture.
1 cup sour cream: Gives the sauce a tangy smoothness and adds luscious creaminess.
1 cup shredded cheddar cheese: Melts beautifully into the sauce and creates that irresistible cheesy pull.
1 can (16 oz) refrigerated biscuits (like Pillsbury Grands): The “bubble” in this bake — the biscuits puff up into golden, fluffy bites of bread that soak in the creamy sauce.
½ cup milk: Thins out the sauce just enough to coat the chicken and biscuits evenly.
½ teaspoon garlic powder: Adds depth and savory warmth.
½ teaspoon onion powder: Enhances the overall flavor with a mild sweetness.
½ teaspoon salt and ¼ teaspoon black pepper: Balances and brightens the taste.
1 cup frozen mixed vegetables (optional): Adds color, texture, and nutrition — peas, carrots, and corn work beautifully here.
Topping
½ cup shredded mozzarella (optional): Sprinkled on top for a gooey, golden finish.
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